Friability Tester
A friability tester is vital for assessing tablet durability during handling, transportation, and storage. It performs accurate friability test to ensure compliance with USP <1216>, EP <2.9.7>, JP <14> pharmacopoeia standards, supporting stringent pharmaceutical quality control. For detailed specifications and additional information, please contact us.
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Find Your Friability Tester
When selecting a friability tester, key factors to consider include the type of drum (e.g., single drum or dual drum), the accuracy of the rotating speed, and compliance with industry standards. A reliable device ensures precise friability test for tablets, providing consistent measurements of tablet durability and weight loss. Advanced features like automated speed control and digital displays enhance accuracy and ease of use, making the tester an essential tool in pharmaceutical quality control.
Friability Tester for sale
Discover reliable automatic tablet friability testers designed for precise and efficient friability test applications. Ensure compliance with industry standards for accurate tablet durability assessment. Contact us for more details.
- Designed for Focused Single-Batch Testing
- Reliable Results with Minimal Setup
- Perfect for Controlled Tablet Durability Analysis
- Dual Testing Capability for Enhanced Accuracy
- Meets Diverse Testing Requirements Effortlessly
- Efficient for Tablets Requiring Consistent Quality
- Handles Multiple Batches Simultaneously
- Optimized for High-Volume Quality Assurance
- Built for Demanding Durability Standards
Friability Tester Technical Parameters
| Parameter | Single Drum Friability Tester | Dual Drum Friability Tester | Triple Drum Friability Tester |
|---|---|---|---|
| Number of Drums | 1 | 2 | 3 |
| Rotation Speed | 25 ± 1 RPM | 20–40 RPM | 20–40 RPM |
| Test Duration | Adjustable up to 99 minutes | Adjustable up to 99 minutes | Adjustable up to 99 minutes |
| Tablet Capacity | Up to 10 tablets | Up to 20 tablets | Up to 30 tablets |
| Control Interface | Digital keypad or touch screen | Touch screen | Advanced PLC control system |
| Compliance Standards | USP <1216>, EP <2.9.7>, JP <14> | USP <1216>, EP <2.9.7>, JP <14> | USP <1216>, EP <2.9.7>, JP <14> |
| Drum Material | Transparent acrylic | Transparent acrylic | Transparent acrylic |
| Power Supply | 220V, 50Hz | 220V, 50Hz | 220V, 50Hz |
| Dimensions (H×W×D) | Approx. 300×250×250 mm | Approx. 350×300×250 mm | Approx. 400×350×300 mm |
| Weight | Approx. 8 kg | Approx. 10 kg | Approx. 12 kg |
Friability Tester Operation Workflow
Preparation and Setup
- Ensure the friability tester is clean and free from debris or residue.
- Check the integrity of the drum(s) for any cracks or damages.
- Verify that the machine is calibrated according to USP <1216> or other applicable pharmacopoeia standards.
- Select the required number of tablets (typically 10) as specified in the test protocol.
- Weigh the tablets accurately using a calibrated balance and record the initial weight.
- Open the drum and place the tablets inside. For dual or triple drum testers, distribute the tablets evenly among the drums if needed.
Running the Test
- Configure the rotation speed (usually 25 RPM, as per pharmacopoeia standards) and set the number of revolutions or test duration using the control panel.
- Close the drum(s) securely to prevent tablets from falling out during operation.
- Start the machine to rotate the drum(s) at the preset speed, causing the tablets to tumble and fall, simulating handling stresses.
- Monitor the process to ensure smooth operation and consistent rotation speed.
Post-Test Procedures
- Stop the machine after the test is complete and carefully remove the tablets from the drum(s).
- Remove any tablet fragments from the drum to ensure accurate results.
- Re-weigh the tablets using the same balance to determine the final weight.
- Calculate the percentage weight loss using the formula:
% Friability = [(Initial Weight - Final Weight) / Initial Weight] × 100 - Verify that the friability is within acceptable limits (typically not exceeding 1%).
Cleaning and Maintenance
- Clean the drum(s) and other machine components to remove any residue or fragments.
- Check the drum’s integrity and replace it if any signs of wear or damage are observed.
- Perform routine maintenance, such as lubricating moving parts and verifying calibration settings.
Frequently Asked Questions
A friability test measures the mechanical strength of tablets to ensure they can withstand handling, transportation, and packaging without breaking apart. This test is critical for maintaining the integrity and quality of pharmaceutical products.
A friability test apparatus is a specialized device used to perform friability tests on tablets. It simulates the stress experienced during handling and transportation by rotating tablets in a drum and measuring the percentage of weight loss.
Modern friability test apparatuses are designed to comply with USP <1216>, EP <2.9.7>, and JP <14>, ensuring precise measurements of tablet durability and adherence to pharmacopoeia standards.
The acceptable limit for friability is typically less than 1% weight loss of the tested tablets. Tablets exceeding this limit may require formulation adjustments or process improvements to enhance durability.
Yes, most friability test apparatuses are versatile and can accommodate various tablet sizes and shapes, ensuring accurate results across different formulations.
Key factors include tablet composition, hardness, and size, as well as the rotation speed and duration set on the friability test apparatus. Proper calibration and maintenance of the apparatus are also crucial for accurate results.
